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Stochasticity Open Seminar April 19, 2017, 14:00

Open Seminars of the Research Group on

 

Stochasticity and Control in the Dynamics and Diversity of Immune Repertories: an Example of Multi-Cellular Co-Operation

 

Wednesday, April 19, 2017, 14:00

at the Israel Institute for Advanced Studies, Room 128

 

 

 

We are not alone: a meeting with your gut microbiome

 

Omry Koren (BIU) 

 

The gut microbiome is the collection of microorganisms including bacteria, archaea, viruses and fungi found within the gut and their genetic information. Our gut microbiota has been shown to have broad effects on our health and well-being, impacting our immune system and metabolism, detoxifying various ingested components, and even effecting behavior. Changes in gut microbiota composition are correlated with different life stages, diet and geographical location, exercise, use of antibiotics and a wide range of disease states. In the next years, this rapidly growing research field is likely to provide more precise interactions and networks connecting hosts with their microbiome.

 

 

Related Research Questions

 

  1. How is the microbiota assembled and maintained over a lifetime?
  2. How personal is each individual’s microbiota?
  3. How does its composition contribute to well-being or disease predisposition and pathogenesis?

 

 

Suggested Reading

 

Structure, function and diversity of the healthy human microbiome.

Human Microbiome Project C

Nature 2012, 486(7402):207-214.

 

Unravelling the effects of the environment and host genotype on the gut microbiome

Spor A, Koren O, Ley R

Nat Rev Microbiol 2011, 9(4):279-290.

 

Conducting a microbiome study

Goodrich JK, Di Rienzi SC, Poole AC, Koren O, Walters WA, Caporaso JG, Knight R, Ley RE. 

Cell 2014, 158(2):250-262.

 

 

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